| Closer | 1st in line | 2nd in line | Updated | Closer | 1st in line | 2nd in line | Updated | ||
| BAL | F Bautista | Cano | Domínguez | 1/10/25 | ATL | Iglesias | Johnson | Dy Lee | 1/10/25 |
| BOS | *Hendriks | *Chapman | *Slaten | 1/10/25 | MIA | *Faucher | *Tinoco | Bender | 1/10/25 |
| NYY | D Williams | Weaver | Hamilton | 1/10/25 | NYM | Ed.Díaz | Minter | Garrett | 1/17/2 |
| TB | Fairbanks | Uceta | Cleavinger | 1/10/25 | PHI | Romano | Kerkering | Alvarado | 1/10/25 |
| TOR | Hoffman | Y García | Green | 1/10/25 | WAS | *J López | *Ferrer | *D Law | 1/11/25 |
| CHW | Anderson | Ellard | Berroa | 1/10/25 | CHC | Hodge | Ty. Miller | Pearson | 1/10/25 |
| CLE | Clase | Gaddis | Smith | 1/10/25 | CIN | Al.Díaz | Pagán | Santillan | 1/10/25 |
| DET | *Brieske | *Vest | *Foley | 1/10/25 | MIL | Tr Megill | Payamps | Uribe | 1/10/25 |
| KC | Erceg | Harvey | Bubic | 1/10/25 | PIT | Bednar | D Santana | Holderman | 1/10/25 |
| MIN | Durán | Jax | Sands | 1/10/25 | STL | Helsley | Fernandez | Romero | 1/10/25 |
| ATH | Miller | Leclerc | Otañez | 1/17/25 | ARI | *Martinez | *Puk | *Ginkel | 1/10/25 |
| HOU | Hader | Abreu | Pressly | 1/10/25 | COL | *Kinley | *Halvorsen | Vodnik | 1/10/25 |
| LAA | Joyce | Burke | Zeferjahn | 1/10/25 | LAD | *Treinen | *Kopech | *Phillips | 1/10/25 |
| SEA | Muñoz | G Santos | Taylor | 1/10/25 | SD | Suarez | Adam | Estrada | 1/10/25 |
| TEX | *C Martin | *R Garcia | Webb | 1/10/25 | SF | R. Walker | Ty. Rogers | Doval | 1/10/25 |
* = closer-by-committee
