| Closer | 1st in line | 2nd in line | Updated | Closer | 1st in line | 2nd in line | Updated | ||
| BAL | Brach | Givens | Bleier | 5/23/18 | ATL | Vizcaino | Minter | Winkler | 5/16/18 |
| BOS | Kimbrel | Kelly | Barnes | 5/14/18 | MIA | Ziegler | Barraclough | Steckenrider | 5/21/18 |
| NYY | Chapman | Robertson | Betances | 5/6/18 | NYM | Familia | Gsellman | Ramos | 5/21/18 |
| TB | Colome | Romo | Alvarado | 5/20/18 | PHI | *Neris | Ramos | Dominguez | 5/22/18 |
| TOR | *Clippard | Tepera | Oh | 5/10/18 | WAS | Doolittle | Kintzler | Kelley | 5/21/18 |
| CHW | *Jones | Fry | Rondon | 5/21/18 | CHC | Morrow | Edwards | Cishek | 5/1/18 |
| CLE | Allen | Miller | Olson | 5/16/18 | CIN | Iglesias | Hughes | Garrett | 5/20/18 |
| DET | Greene | Jimenez | Farmer | 5/16/18 | MIL | Knebel | Hader | Jeffress | 5/22/18 |
| KC | Herrera | Keller | McCarthy | 5/19/18 | PIT | Vazquez | Feliz | Rodriguez | 5/17/18 |
| MIN | Rodney | Reed | Duke | 4/27/18 | STL | Norris | Hicks | Tuivailala | 5/23/18 |
| HOU | Giles | Devenski | Peacock | 5/19/18 | ARI | Boxberger | Bradley | Hirano | 4/23/18 |
| LAA | *Anderson | Parker | Johnson | 5/21/18 | COL | Davis | Ottavino | Shaw | 5/19/18 |
| OAK | Treinen | Casilla | Petit | 5/18/18 | LAD | Jansen | Fields | Baez | 5/21/18 |
| SEA | Diaz | Nicasio | Vincent | 5/16/18 | SD | Hand | Yates | Stammen | 4/20/18 |
| TEX | Kela | Martin | Diekman | 5/21/18 | SF | Strickland | Watson | Dyson | 5/18/18 |
* = closer-by-committee
