| Closer | 1st in line | 2nd in line | Updated | Closer | 1st in line | 2nd in line | Updated | ||
| BAL | *Valdez | Harvey | Scott | 9/21/20 | ATL | Melancon | Greene | Smith | 9/10/20 |
| BOS | Barnes | Brasier | Valdez | 9/11/20 | MIA | Kintzler | Boxberger | Garcia | 9/12/20 |
| NYY | Chapman | Britton | Ottavino | 9/3/20 | NYM | Diaz | Wilson | Familia | 9/19/20 |
| TB | *Anderson | Castillo | Drake | 9/27/20 | PHI | *Neris | Hunter | Phelps | 9/20/20 |
| TOR | *Bass | Dolis | Cole | 9/27/20 | WAS | Hudson | Harris | Suero | 9/27/20 |
| CHW | Colome | Marshall | Bummer | 9/27/20 | CHC | Jeffress | Kimbrel | Adam | 9/20/20 |
| CLE | Hand | Karinchak | Wittgren | 8/29/20 | CIN | Iglesias | Bradley | Garrett | 9/23/20 |
| DET | B.Garcia | Soto | Cisnero | 9/20/20 | MIL | Hader | Williams | Claudio | 9/1/20 |
| KC | *Barlow | Hahn | Staumont | 9/26/20 | PIT | Rodriguez | Turley | Stratton | 9/26/20 |
| MIN | *Rogers | Romo | May | 9/5/20 | STL | *Miller | Reyes | Gallegos | 9/23/20 |
| HOU | Pressly | Scrubb | Raley | 9/20/20 | ARI | Crichton | Guerra | Bergen | 9/17/20 |
| LAA | *Mayers | Pena | Buttrey | 9/24/20 | COL | Bard | Givens | Almonte | 9/25/20 |
| OAK | Hendriks | Soria | Diekman | 9/4/20 | LAD | Jansen | Treinen | Baez | 9/27/20 |
| SEA | Hirano | Ramirez | Misiewicz | 9/8/20 | SD | Rosenthal | Pomeranz | Pagan | 9/11/20 |
| TEX | Montero | Hernandez | Martin | 9/7/20 | SF | *Watson | Rogers | Selman | 9/27/20 |
* = closer-by-committee
